m6A-dependent mRNA processing promotes translation and decay, and affects splicing

by Paul | Dec 7, 2016

Post-transcriptional gene regulation by mRNA modifications Boxuan Simen Zhao, Ian A. Roundtree & Chuan He Nature Reviews Molecular Cell Biology (2016) doi:10.1038/nrm.2016.132

m6A alters RNA structure to enhance HNRNPC binding

by Paul | Dec 7, 2016

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions Nian Liu, Qing Dai, Guanqun Zheng, Chuan He, Marc Parisien & Tao Pan Nature 518, 560–564 (26 February 2015) doi:10.1038/nature14234

m6A switches

by Paul | Dec 7, 2016

N6-methyladenosine–encoded epitranscriptomics Nian Liu & Tao Pan Nature Structural & Molecular Biology 23, 98–102 (2016) doi:10.1038/nsmb.3162 Received 14 July 2015 Accepted 17 December 2015 Published online 03 February 2016

YTHDF2 selectively binds m6A-containing RNA.

by Paul | Dec 7, 2016

N6-methyladenosine-dependent regulation of messenger RNA stability Xiao Wang, Zhike Lu, Adrian Gomez, Gary C. Hon, Yanan Yue, Dali Han, Ye Fu, Marc Parisien, Qing Dai, Guifang Jia, Bing Ren, Tao Pan & Chuan He Nature 505, 117–120 (02 January 2014)...

Development of m1A-seq to map a newly identified constituent of mammalian mRNA

by Paul | Dec 7, 2016

Figure 1: Development of m1A-seq to map a newly identified constituent of mammalian mRNA. The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA Dan Dominissini, Sigrid Nachtergaele, Sharon Moshitch-Moshkovitz, Eyal Peer, Nitzan Kol, Moshe Shay Ben-Haim,...